摘要
我们测定了149例眼球穿通伤患者血清免疫球蛋白和C_3含量,发现患者血清IgG、IgM含量显著高于对照组,除15岁以下组和46岁以上组外,患者血清IgA含量也显著高于对照组,患者与对照组的C_3含量无显著差异;血清IgG的水平与慢性炎症的严重程度呈正相关;眼球穿通伤7天后,血清IgG、IgA、IgM含量显著升高,并长期维持于高水平,与慢性炎症过程相平行;眼内异物患者血清IgG含量显著高于单纯眼球穿通伤患者。这些结果表明,眼球穿通伤后慢性炎症是由多种因素造成的持续地自身免疫反应所致。根据本文结果,讨论了参与慢性炎症形成的各种因素以及如何预防和治疗等问题。
Serum IgG,IgA,IgM and C_3 were measured on 149 patients with penetrating eye injury and 150 healthy subjects were as control. The level of lgG and IgM increased significantly in patients compared with controls. The level of IgA in patients was also significantly higher than that in controls except the groups less than 15 years old and more than 46 years old. No difference in serum level of C_3 was found between patients and controls. The serum immunoglobulins(IgS)increased in 7 days after injury, maintained for along time and correlated to the ocular inflammation. The level of IgG in patients with intraocular foreign body was much higher than that in those with simple penetrating eye injury. It was strongly suggested that the uveitis following penetrating eye injury was mediated by persistent autoimmune reaction. The influential and prevention treatment of the uveitis were discussed.
出处
《眼外伤职业眼病杂志》
北大核心
1989年第2期65-70,共6页
Journal of Injuries and Occupational Diseases of the Eye with Ophthalmic Surgeries
