摘要
人正常房水白蛋白及免疫球蛋白的测定,对评价血房水屏障功能及探讨多种眼病的发病机制有重要意义。但是,由于正常房水不易获得,限制了这方面的研究。以往均以尸体眼房水或白内障眼房水做为“正常房水”
The level of Immunoglobulins(Igs) and Albumin(Al) in aqueous humor was measured on 38 healthy subjects. To our knowledge, it is frist time to measure normal aqueous Igs. Aqueous Al and IgG was 7.96mg% and 4.44mg%, respectively. No measurable Ig(?) IGM and C3 was found in all subjects. With the increase of age, the level of Al was significantly elevated, but the increase of IgG failed to reach significance statistically. The aqueous Al and IgG in healthy subjects was markedly lower than in patients with cataract and dead bodies. The aqueous proteins filter coefficient of healthy subjects was also smaller than that of patients with cataract. Therefore it is unreasonable to take the aqueous humor from dead or patient with cataractf or normal. Comparing several ratios about serum and aqueous Al and IgG, we believe that there was 'excessive IgG' in aqueous humor of healthy person, but we know little about its meaning. With aging the aqueous Al fillter coefficient increased significantly, showing decreased function of blood-aqueous barrier, which may contribute to the development of senile cataract.
出处
《眼科研究》
CSCD
1989年第1期1-4,共4页
Chinese Ophthalmic Research
