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槽式对流免疫电泳法检测可提取性核抗原抗体的研究 被引量:4

Investigations on CIE method in the detection of anti ENA antibodies
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摘要 用引进的槽式对流免疫电泳法(槽CIE)和国内常规的免疫双扩散法(ID),同时对89例病人血清可提取性核抗原(ENA)的抗体进行了测定和比较。槽CIE法图像清晰、沉淀线呈弧型,结果明显比ID法容易判断,ENA抗体阳性病人血清的检出率非常显著地高于ID法(P<0.001),抗SM、RNP、SSA、SSB等每种抗休的检出率也均高于ID法,其中前3种差异非常显著(分别P<0.01,P<0.01,P<0.001)。 For the detection of anti ENA antibodies an improved method of counterimmu-noeletrophoresis(Trough-CIF)was introduced and compared with the routine test of double im-munodiffusion( ID).Eighty nine patients sera were tested by these two methods.The results were shown as follows.(1) Picturcs and results in Trough-CIE were clearer and easier to be judged thanin ID(2).Detectable rate of anti ENA positive sera was significantly higher in Trough-CIE than inID tP<0.001).(3)Each of four kinds of ENA antibodies(anti-SM,anti-RNP,anti-SSA andanti-SSB)was more frequently detected by Trough-CIE than by ID,especially the first three kindsof antibod000(P<0.01,P<0.01,P<0.001 respectively)
出处 《白求恩医科大学学报》 CSCD 1995年第2期203-205,共3页 Journal of Norman Bethune University of Medical Science
关键词 对流免疫电泳 ENA抗体 抗体 counterimmunoelectrophoresis(CIE) ENA antibodies。
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  • 1汪利平,李宁,武建国.抗ENA抗体的检测及临床初步应用[J]江苏医药,1984(03).

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