摘要
作者收集了1978─1987年十年间美国洛杉矶市全部494鼻咽癌病例,对其中14岁以下儿童病例作一分析。洛杉矶市鼻咽癌发病率较低(0.66/105),而儿童病例却相对多见(1.82%),其中又以黑人的构成比更高(占全部黑人病例10.2%),黑人儿童病例预后较差(本组死亡病例均为黑人);在美国、非洲的多篇报道中均有相似结果。相反在鼻咽癌高发的中国人和高发区之一的广东省,儿童病例却极为少见(0.1%)。通过本组及世界各地报道材料认为:在儿童鼻咽癌病因发病学上,遗传因素可能起着主要作用。
cases of
nasopharyngeal carcinoma(NPC) were collected from 1978 to 1987 and
analysed who was under 14 years old at Los Angeles. The incidence
rate of NPC in Los Angeles was low( 0. 66/ 1 0°) but the disease in
children were more common relatively(accounted for 1. 82%),
especially in black(accounted for 10.2%). The prognosis was poor for
black chil-dren. There were some similar reports in US and Africa.
Contrary, NPC in childhood was rare in the high risk area such as
Guangdong, Hong-kong and in the high risk population such as
Chin-ese. According to this series and another reports the author
thinks that genetical factor plays a main role on occurence of NPC.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1995年第5期346-348,共3页
Chinese Journal of Cancer
关键词
儿童
鼻咽肿瘤
种族
遗传
Nasopharyngeal Carcinoma Chicdhood Ethnic Heredity