摘要
本文回顾性分析初治鼻咽癌３２０例，以了解放疗全程长短对放疗效果的影响，病例按放疗设计分为四组，放疗全程时间因素按线性平方公式，计入生物学效应剂量（ＢＥＤ）。以１、３年局部复发率和１、３年生存率作为指标比较各组疗效。结果表明：放疗疗效与疗程的延长呈负相关，复发率上升。生存率下降：与各组的ＢＥＤ值呈正相关，ＢＥＤ值高，疗效相对较好，连续组比分段组全疗程时间平均缩短１２天，对于相同ＭＴＭ分期患者，其３年生存率平均提高约１０％，结论是：放疗全程时间长短对放疗疗效有明显影响。
NPC patients had their first radiotherapy courses at our
departmentfrom Jun.1989 through Sept. 1990,the patients were divided
into four groups according to thetreatment schedules, and the impact
of radiotherapy course length on the treatment results wascompated
with 1-,and 3-year loco-regional recurrent rates, and 1-, and 3-year
survivalrates,course length factor was considered with a LQ model
formula by biolugical effective dose(BED ) values. The results
indicated that there was a negative interrelation with polonged
courseduration but a positive one with BED values. Continuous group
treatment course was average 12days shorter than the split-course
one, and its treatment results were about 10% higher for thesame
stage patients.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1995年第5期373-374,共2页
Chinese Journal of Cancer
