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人脑胶质瘤生物导向影像定性诊断与X-CT的对比分析 被引量:1

CLINICAL ANALYSIS OF TARGETING DIAGNOSIS OF HUMAN GLIOMAS
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摘要 用自制的生物导向显像剂131I—SZ39静脉注射于40例经X—CT证实的颅内占位患者,SPECT扫描出现阳性免疫复合物时,在占位区域内呈现红色斑块,藉此对胶质瘤进行定性诊断,并与X-CT进行对比.分析其定性诊断效能。结果其敏感性92%,正确性82%,阳性预报价值81%,阴性预报价值91%。明显优于X-CT。 patients with X-CT confirmed intracranial space occupying di- seases were intravenously injected with the targeting image agent 131 I-SZ39 pepared in our laboratory. With SPECT scanning, the positive complex will display a red colour in the space occupying area which confirms the diagnosis of glioma. The differential diag- nosis efficiency of SPECT targeting diagnosis was also compared with that of X-CT. The result showed that the sensitivity rate is 92%, the accurate rate 82%, the positive predication rate 81 %, and the negative predication rate 91 %, indicating that the targe- ting diagnosis with SPECT is much more reliable than X-CT.
出处 《癌症》 SCIE CAS CSCD 北大核心 1995年第4期271-273,共3页 Chinese Journal of Cancer
基金 本研究为工业"八.五"攻关课题已通过部级鉴定。
关键词 脑肿瘤 生物导向 影像学诊断 胶质瘤 CT Brain tumor Monoclonal antibody Radioactive isotope Image diagnosis
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参考文献6

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同被引文献6

  • 1Chomczynski P,Saachi N.Single-step method ofRNA isolation by acid guanidinium thiocyanatephenol-chloroform extraction. Analytical Biochemistry . 1989
  • 2Pluckthun A.Antibody engineering f advances fromthe use of Escherichia colt expression systems. Journal of Biotechnology . 1991
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