摘要
用祛痰宁治疗呼吸道疾病386例,其中双盲 法治疗51例;并与病情相似的花生油安慰剂组40 例,牡荆丸组85例及进口稀化粘素组20例对照;口服 祛痰宁374例中,总有效率为85.6％;而安慰剂组总 有效率为25％;牡荆丸组为55％;经ridit分析,祛痰 宁组明显优于安慰剂组与牡荆丸组;但与进口稀化 粘素组总疗效近似(85％,P>0.05)。祛痰宁具有 较强的促进排痰,减低痰的粘稠度,起效快,副反 应少,尤其适用于年老,体弱,小儿及重症病人排 痰困难者。
This paper reports 386 patients with respiratory tract diseases accompanying expectorative difficulty treated with cineole compositus(Qu-tan-ning) 300 mg qid for 7-10 d as a course.In double blind studies 51 patients were compared to 40 patients treated with placebo (peanut oil), 85 patients caps, olei Vitex negun-do and 20 patients myrtenol, under similar conditions. The total expectorant efficacy of cineole compositus group ,was 85.6%,and 88% in double blind group. Cine-ole compositus groups were much higher than that of placebo group(25%, P< 0.01),and caps.olei Vitex negundo group(55%, P<0.01), and similar to myrtenol group(85%,P>0.05).The onset of effects is rapid with few adverse effects. It is a good expectorant, especially suitable for those old, weak, children and intensive care unit patients with difficulty in expectoration.
出处
《新药与临床》
CSCD
北大核心
1989年第6期343-346,共4页
关键词
祛痰宁
呼吸道疾病
复方
桉油醇
cineole compositus
respiratory tract diseases
Chinese herbal drugs
