摘要
作者发现用抗精神病药治疗的10080例住院病人中,有13例诊断为本症,其发生率为1.28‰。病例多发生于青年人,男、女相等,以精神分裂症病人为多,均使用抗精神病药治疗并支持本症与药物有关。作者认为,在鉴别诊断中应注意与精神分裂症紧张型及非典型脑炎相鉴别。本文报道的13例在停药及综合治疗后全部治愈,不支持以往认为本症死亡率颇高的看法。
The writers found 13 patients diagnosed as antipsychotic malignant syndrome (AMS)among 10 080 antipsychotic treated inpatients. The incidence of AMS was 1.28‰. These patients were found commonly in young adults and had a cqual ratio in male and female. Most of the patients diagnosed as AMS were schizophrenic patients treated with antipsychotics, which Supports the view that AMS is related to medication. The writers held that attention should be paid to differentiate it from schizophrenic catatonia and atypical encephalitis. The 13 patients reported here had all been cured after stopping the antipsychotics and applied ordinary therapies. This does rot support the view that the prognosis of AMS is poor.
出处
《新药与临床》
CSCD
北大核心
1989年第4期210-212,共3页
关键词
安定药
抗精神病药
发病率
syndrome
major tranquilizing agents
morbidity
