摘要
本文采用紫外分光光度法对国内六厂家+批号的甲硝唑片进行了体外溶出度测定。实验数据经计算器检Weiboll分布数学模型处理后,提取溶出参数T50、Td、m进行方差分析,各药厂产品间存在显著性差异。(P<0.01)。
The dissolution rated from ten batches of metronidazole tablets producted by six pharmaceutical factries was studied with rotation basket and UV spectrophotometry it was found that the T50 Td and m of those samples had obviousdifference (P<O. 01).
出处
《航空航天医药》
1995年第2期68-69,共2页
Aerospace Medicine
关键词
甲硝唑
片剂
溶出度
紫外分光光度法
metronidazole dissolution rate UV spectrophotometry Weiboll distribution.