摘要
探讨有关内科危重症并多器官功能衰竭（MOF）的定义、诊断、临床分型及其与预后的关系。MOF的基本诊断条件应具有：致病因素＋全身炎症反应＋器官功能受损。它可分为普通型和危重型。本组报道的156例中，普通型70例，存活59例，死亡11例；凶险型86例，存活9例，死亡77例。凶险型发生死亡的相对危险度（RR）为4．81。95％的可信区间在3．44－6．69。结果提示，MOF预后与临床分型关系更为密切。把MOF分成两型，对早期诊断和判断预后有重要意义。
In this paper, an attempt is made to discuss the definition, diagnosis .clinical classification and the relationship between prognosis and clinical classification of multiple organ failure (MOF) in internal medicine. We suggest that diagnosis of MOF include pathogenic factors,systemic inflammation response and organ failure. It might be classified into two clinial patterns: common and criticcal. 156 cases were analysed, retrospectively,who are with various infection,shock and physical-chemical factors, systemic inflammation response and in whom organic failure was found in two or more than two organs in succession or at the same time. 70 cases were identified as common pattern of MOF,of whom 59 were survival and 11 dead. Mortality was 15. 7%. The other 86 cases were identified as critical pattern,of whom 9 were survival and 77 dead. Mortality was 89. 5%. The relative risk (RR) of death in critical pattern was 4. 81:the 95 % confidence interval was ranged 3. 44-6- 69. The result showed that outcome of MoF was not only decided by the number of affected organs, but also correlated more closely with clinical patterns. We believe that classification of MOF is very important in making early diagnosis and measuring prognosis.
出处
《急诊医学》
CSCD
1995年第4期203-207,共5页
关键词
多器官衰竭
全身炎症反应
分型
内科危重病
诊断
multiple organ failure(MOF) systemic inflammation response pathogenic factors critical ill patient
