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新型双泵复苏术的基础研究:以胸骨按压为主体的双泵复苏术的血液动力学研究 被引量:9

The Hemodynamic Study of The Chest Compression Assisted with Enhanced External Counterpulsation
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摘要 胸部按压放松期辅以体外膈肌起搏(EDP)和增强型体外反搏(EECP)的双泵复苏木(EDCPR)对8条犬室颤1分钟后,随机先后予以标准心肺复苏术(SECPR)与EDCPR进行自身对照实验研究。实验结果:EDCPR较SECPR显著提高升主动脉收缩压(P<0.05),舒张压(P<0.01)。而右房舒张压平均值来显著性升高(P>0.05)。冠脉有效灌流压(CPP)显著增加(P<0.01)。提示EECP使动脉血运流升高舒张压,EECP的促进静脉回流与EDP的胸腔负压形成配合,静脉回流血吸入肺循环并流向左心,不升高右房压又增加前负荷,主动脉压收缩压升高。EDCPR既产生了有效的人工通气、调动了大小循环;又较好地改善了心肌血供。 It was put forward the new CPR named as "EDCPR" which is chest compres-sion assisted with enhanced external counterpulsation (EECP) and external diaphragm pac-ing (EDP) at relaxed stage. After one minute of ventricular fibrillation, standard externalCPR (SECPR)and EDCPR were performed in random order in eight dogs. Results:EDCPRproduced the systolic and diastolic pressures of ascending aorta higher than SECPR (P <0. 05). It was not significantly different in mean right atrial diastolic pressure between ED-CPR and SECPR (P > 0. 05). EDCPR improved coronary perfusion pressure (CPP) that re-flects myocardial perfusion much more than SECPR (P< 0. 01). Authors considered thatEECP squeezes sequentially the blood of Iower body retrograde toward the heart and brain so that aortic diastolic pressure was augmented and venous return was increased. EDP produces negative intrathoracic pressure and suckes venous return from right atrium to pulmonary vas-culature and left heart to cycle effectively pulmonary circulation and to decrease right atrial pressure. EDCPR produced effective artificial ventilation and systematic/pulmonary circula-tion. Therefore, aortic diastolic pressure was increased and right atrial pressure did not rise so that myocardial blood supply was improved.
出处 《急诊医学》 CSCD 1995年第3期140-144,共5页
基金 国家自然科学基金
关键词 心肺复苏 胸骨按压 血液动力学 双泵复苏 cardiopulmonary resuscitation external counterpulsation external diaphragm pacing dogs hemodynamics
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  • 1谢秉煦,中华结核和呼吸杂志,1988年,11卷,3期,156页

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