摘要
本文报道24例急性心肌梗死（AMI）患者、16例心绞痛（AP）患者和38例健康人群的体液免疫指标的检测结果并作了比较。结果发现前两者IgG、C3和循环免疫复合物（CIC）水平明显高于后者，而且AMI组的IgG、C3和CIC水平也明显较AP组要增高。AMI组中，大面积梗死的IgG、C3较局限性梗死者要明显增高。进一步证实了免疫反应在冠心病发生、发展过程中起着重要作用，其反应程度与心肌梗死面积大小有密切关系。提示体液免疫水平可能作为判断冠心病（尤其是AMI）病情严重程度的指标之一。本文尚对冠心病的免疫反应机理进行了初步探讨。
The humoral immune function of 24 patients with acute myocardial infarcticn(AMI) was detected, comparing to that of 26 patients with angina pectoris (AP) and 38healthy persons. The results showed that the patients with AMI and the patients with APhad significantly higher levels of IgG, C3 and circulating immune complex (CIC) in theirserum than the healthy person, and the levels of IgG,C3 and CIC of patients with AMI werehigher than that of patients with AP. Further study showed that the changes of humoral immune function were probabely correlated with the range of infarcted myocardium. This suggested that the levels of humoral immune function could act as one of markers of severity ofAMI. The immunological pathogenesis of coronary atherosclerotic heart disease were discussed in this article too.
出处
《急诊医学》
CSCD
1995年第2期85-87,共3页
关键词
急性
心肌梗死
免疫球蛋白G
体液免疫
acute myocardial infarction IgG C_3 circulating immune complex (CIC)
