摘要
本文报道50例癌症病人应用康泉控制胃肠道反应的临床观察效果．结果表明，康泉对恶心、呕吐的控制率分别为96％、94％，有64％的病人不影响进食及日常生活，用药第一天84％的病人无呕吐发生，止吐有效率为94％．大多数病人使用1次康泉即可制止呕吐，且作用可维持≥5天．未发现康泉有明显的副作用．
Toxicity of the gastrointestinal tract is a common side effect in patients with maignancies who received chemotherapy.Sometimes,patients aren't tolerant of chemotherapy and can't receive chemotherapy beause of severe nausea and vomiting. This study reports the effectivenere of granisetron(kytril)in the prevention of chemoherapy-related gastrointestinal toxicity in 50 patients. Results showed that the response rates of the prevention of nausea and vomiting were 96% and 94K respetively. 64% of patients can perform normal activity and have normal appetite, 84% of patients had no vomiting after the administration of granisetron on the first day of treatment and the response rate was 94%. Vomiting can be prevented after the administration of a dase of 3mg granisetron. Furthermore, the effectiveness can be maintained over five days. In the most of patients no obvious side effects were observed.
关键词
止吐药
康泉
反应率
药物副作用
肿瘤
Chemotherapy/Toxicity Antiemetic drugs Granisetron Response rates
