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大输液生产车间洁净室与药液过滤系统消毒效果调查报告

INVESTIGATION ON EFFICACY OF DISINFECTION OF CLEANING ROOM AND FILTRATION SYSTEM IN WORKSHOP PRODUCING INFUSION PREPARATIONS
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摘要 热原反应可给患者带来严重不适和痛苦,甚至危及生命。在制备大输液过程中,热原污染途径多来源于注射用水、容器、设备、环境、原料药物及制备过程。目前,国内有些医院的灭菌制剂室往往达不到药品生产和质量管理规范(GMP) Contamination of infusion fluids in hospital can cause pyrogcn rcaction. In order to improve the aseptic condition in preparing the infusion fluids in hospitals, a series of disinfection and stcrilization mcasures for cleaning room and infusion fluid filtration system were established. It was indicated by bacteriological examination that the measurcs adopted could effectively reduce the number of bacteria in air of cleaning room and cnsure sterilization of infusion fluids.
作者 孙为 李新生
出处 《消毒与灭菌》 北大核心 1989年第4期200-202,共3页
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