摘要
采用大剂量卡铂并自体骨髓移植（ＡＢＭＴ）治疗５例小细胞肺癌（ＳＣＬＣ）患者，其中男性４例．女性１例，年龄１９～５５岁，发病到开始ＡＢＭＴ时间３～１４个月。５例中４例已接受过不同方案的常规诱导化疗，１例手术切除肺主体病灶。开始大剂量化疗时３例部分缓解（ＰＲ），另２例对常规治疗无明显反应，卡铂剂量为５６０～１３７５ｍｇ／ｍ２。大剂量化疗后４例完全缓解（ＣＲ），１例无明显变化，ＣＲ持续时间１．５～１８个月。
Abstract The efficacy of high dose carboplatin therapy with auotologous bone marrow transplantation (ABMT)was studied in five patients with extensive small cell lung canoe (SCLC). Among of them,4 males and 1 female, the averageage was 40. 6 years (range, 19 to 55 years), the median duration from dignosis to ABMT was approximately 8. 6 months (range, 3 to 14 months). Four patients had received prior induction chemotherapy and one patient received the surgical therapy. At the begining of high dose therapy, 3 patients had achived partial remission (PR) and other patients had not responded to routine chemotherapy. The dose of carboplatin ranged from 560 to 1375 mg/m2 At the end of high dose carboplatin therapy with ABMT, there were 4 complete remission (CR) and one case was not changed. The duration of CR ranged from 1. 5 to 18 months
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
1995年第5期296-299,共4页
Cancer Research on Prevention and Treatment
