摘要
本文对５７例良性肿瘤、５２例恶性实体瘤患者和８０例正常人血浆中Ｌｐ（ａ）和ＴＣ、ＴＧ、ＡｐｏＢ、ＡｐｏＡ－Ⅰ的水平进行了比较。结果发现，上述指标在良性肿瘤与正常人之间无统计学差异。恶性实体瘤患者的Ｌｐ（ａ）水平明显高于良性肿瘤患者和正常人，ＴＣ水平明显低于良性肿瘤患者和正常人，ＡｐｏＢ和ＡｐｏＡ－Ⅰ明显低于正常人。本文认为，Ｌｐ（ａ）可能通过影响凝血系统而对肿瘤的生长和转移发挥一定的促进作用，Ｌｐ（ａ）和ＴＣ水平有可能成为恶性肿瘤辅助诊断的生化指标。脂质、脂蛋白和载脂蛋白与肿瘤的关系，值得进一步研究。
The plasma Level of lipoprotein (a) (LP (a) ) , total cholesterdol (TC), triglyceride (TG),Apolipoprotein B (ApoB) and ApolipoproteinA-I (ApoA-I) in 57 patients with benign tumors,52 patients with malignant parenchymatous tumors and 80 normal controls were observed. The results showed that there were no statistic differences of the indices observed between benign tumor patients and normal controls. Patients with malignant parenchymatous tumors had a higher LP(a) and a Lower TC level compared with that in the other two groups, and a lower level of ApoB and ApoA- I with that in normal controls. It is considered that Lp (a) might excert a certain promotive effect on the growth and metastasis of tumors by affects the coagulating system. It is possible that Lp (a ) and TC might be used as biochemical indices in accessory diagnosis of malignant tumors.The relationship between tumors and Lipids, Lipoproteins or apoLipoproteins is worth further study.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
1995年第4期232-233,共2页
Cancer Research on Prevention and Treatment
