摘要
5a内院内肺部感染160例,均为有严重疾病,并伴有长期不规则使用广谱抗生素、激素及抗肿瘤药物的患者。从痰分离出387株致病菌,G ̄+球菌69株,占17.8%;G ̄-杆菌296株,占76.5%;类酵母菌22株,占5.7%。致病菌以克雷白杆菌、绿脓杆菌最多,其次为阴沟杆菌、大肠杆菌、金黄色葡萄球菌。从耐药性测定说明对青霉素、四环素、红霉素、卡那霉素、庆大霉素、氯霉素等耐药率为70%~100%;对丁胺卡那、头孢唑啉耐药率为20%~40%。直接死于肺内感染34例,死亡率21.3%。
cases of nosocomial or hospital-acquired pneumonia from 1984 to 1989
were reviewed retrospectively.Predisposing factors include severe
systemic diseases, ong-term and irregular use of broad-spectrum
antibiotics,corticosteroid and antineoplastic agents 387 strains of
pathogen were isolated from sputum, 69 strains of gram-positive
cocci(17.8%), 296 strains of gram-negative rods(76.5%),22 strains of
yeasts(5.7%).Themost common species were Klebsiella pneumoniae and
pseudomonas aeruginosa, followed by bacillus cloacae, bacillus coli
and staphylococcus aureus.The percentage of drug-resis-tant to
penicillin , tetracycline ,erythromycin ,kanamycin ,gentamycin ,and
chloromycetin was 70%~100%,and to amikacinl cefazolin was 20%~40%,
34 patlents died from pul-monary infection.The mortality of
hospital-acquired pneuminia was 23%.
出处
《中日友好医院学报》
1995年第1期12-15,共4页
Journal of China-Japan Friendship Hospital