摘要
为分析阴沟肠杆菌在我科的高检出率和高耐药性,随机留取了1990年6月～11月间的32株自烧伤患者血液及感染部位分离所得的阴沟肠杆菌,调查了该菌对21种抗菌药物的敏感性,并对其质粒图谱进行了分析。结果表明,32株中的29株对9种以上的抗生素耐药,另3株菌耐药性稍弱;对32株阴沟肠杆菌中的27株进行的质粒图谱分析表明,3株耐药性稍弱的菌株中不含任何质粒,另外24株菌的质粒图谱依菌株而异,但都含有一个分子量约80kb的质粒。此80kb质粒明显地与我科阴沟肠杆菌的高检出率和高耐药性有关。
In view of a high positive isolation rate and resistance to antibiotics of Enterobacter cloacae in our department, 32 strains of E. cloacae, which were isolated from blood and infected wounds of burned patients from June through November 1990, were randomly selected to determine their susceptibility to 21 antibiotics and their plas- mid patterns. It was found that 29 of 32 strains were resistant to at least nine antibi- otics, while the other three strains were relatively sensitive. 27 of 32 strains of E.cloa- cae were tested for plasmid, and among them, three strains (relatively sensitive to an- tibiotics)contained no plasmid. The plasmid patterns of the other 24 isolates varied with strains, but all of them had a 80 kb plasmid. The 80 kb plasmid was obviously related to the high isolation rate and high resistance to antibiotics of E. cloacae isolated in our department.
