摘要
建立血小板膜糖蛋白(GP)的流式细胞术(FCM)检测方法并初步用于诊断血小板无力症(GT)。结果表明:FCM不但能灵敏、快速、准确、特异地检测单个或亚群血小板膜GP的变化,而且很容易鉴别GT及其杂合子携带者,为GT的诊断提供了一种新方法。
he authors have developed a method for detecting platelet membrane glycoproteins (GP)usingflow cytometry(FCM ),and three cases of Glanzmann' s thrombasthenia(GT)were diagnosed by thisassay. The results showed that FCM ernployed for detecting the changes of GP of individual or subpopu-lations membrane is not only sensitive, rapid, accurate and specific, but also easy for the identification ofGT from it's heterozygote carriers, and thus provides a new method for diagnosis of GT.