摘要
用湿热灭菌法和干热灭菌法测定新癀片半成品中5种污染霉菌孢子的热致死温时,结果表明短柄曲霉(Aspergillus brevipes)8 201菌株的耐热性最强。以湿热法和干热法灭菌的热致死温时分别为60℃/30min和80℃/100min,通过加热灭菌效果的统计学推算,建立新癀片的科学灭菌方法。
Thermal death point (TDP) and time (TDT) to the spores of five fungal species isolated from half-finished product of Xin Huang Pian, a Chinese traditional drug, were examined by dry heat method and moist heat method. The results showed that Aspergillus brevipes 8 201 was most resistant to thermal treatment: TDP value by moist heat and TDT value by dry heat were 60℃/30 min and 80℃/100min respectively. The efficient sterilization method for Xin Huang pian was established after analysis of sterilisation efficiency. Asp.brevipes was proposed as test organism for sterilization control.
出处
《厦门大学学报（自然科学版）》
CAS
CSCD
北大核心
1989年第5期554-558,共5页
Journal of Xiamen University：Natural Science
关键词
固体中成药
短柄曲霉
热致死温时
Solid Chinese drugs, Aspergillus bsevipcs, Thermal death point and time
