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肾移植术前透析患者抗体水平的检测 被引量:1

The study of antibody level in hemodialytic patients before kidney transplantation
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摘要 对459份肾移植前透析患者随机血清进行了抗体水平调查,对其中的72份淋巴细胞毒高敏感患者血清做了抗体检测。结果表明,首次移植前血清抗体阳性率为20.6%,再次移植前血清抗体阳性率75%。72份高敏感患者血清无论在4℃或在37℃均对B淋巴细胞反应,而对T淋巴细胞反应则少。因排斥而切除移植肾的透析患者其抗B淋巴细胞毒抗体高于输血和妊娠所致的淋巴细胞毒抗体。认为系统地了解肾移植受者的抗体水平,对移植肾的存活与进一步提高移植肾的存活率具有一定的意义。 Random serum samples from hemedialytic renal transplant candidates were examined. 72 samples from lymphocytotoxic high-sensitized patients were tested for antibody . The results showed that the positive rate of serum antibody was 20. 6% before the first transplantation, and 75% before retransplantation. Regardlessly in 4℃ or 37℃,all samples from high-sensitized patients reacted to B lymphocyte, but few of them reacted to T lymphocyte.The titer of B lymphocytotoxic antibody from hemodialytic patients with graft loss due to rejection was higher than that from ones whose lymphocyte antibody is caued by blood transfusion or pregnancy.
出处 《中华器官移植杂志》 CAS CSCD 1995年第3期104-105,共2页 Chinese Journal of Organ Transplantation
关键词 血液透析 抗体 肾移植 手术前 检测 Hemodialytic Antibody
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同被引文献6

  • 1贾保祥,刘宏,张玉海,吴国荃.淋巴细胞抗体高敏感患者与肾移植[J].中华泌尿外科杂志,1995,16(7):400-402. 被引量:1
  • 2于立新,徐健,白喜文,罗永礼,马俊杰,邓文峰,叶桂荣.移植肾超急性排斥反应临床探讨[J].临床泌尿外科杂志,1995,10(2):71-73. 被引量:3
  • 3SALMELAK.Vin Wille Brand E,Kyllonen L.et al. The associationof HLA-DR antigens with acuate steroidresistant rejection and poorkidney graft survival TRANSPLANTATION 1991;51(4):768~771
  • 4Allen N,Dyer P,Harris k,et al.Effects of Plasma exchange onimmunoglobulins complement and immune complexes in renal trtnsplantrecipients. TRANSFUS TECHNOL,1982;3(2):157~162
  • 5Vangelcst A,Erasca G,M.and bonomini V,Parameters for indicationof plasmaheresis and the interpretatior of reswts CLIN NEPHROL,1986;26(1):564~569
  • 6Haberel H,Bulut O.Sert S,et al.Treatment of steroidresistantrenal allograft rejction and okt 3 and plasmaheresis RENAL FAIL 1991;13(1):43~47

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