摘要
对459份肾移植前透析患者随机血清进行了抗体水平调查,对其中的72份淋巴细胞毒高敏感患者血清做了抗体检测。结果表明,首次移植前血清抗体阳性率为20.6%,再次移植前血清抗体阳性率75%。72份高敏感患者血清无论在4℃或在37℃均对B淋巴细胞反应,而对T淋巴细胞反应则少。因排斥而切除移植肾的透析患者其抗B淋巴细胞毒抗体高于输血和妊娠所致的淋巴细胞毒抗体。认为系统地了解肾移植受者的抗体水平,对移植肾的存活与进一步提高移植肾的存活率具有一定的意义。
Random serum samples from hemedialytic renal transplant candidates were examined. 72 samples from lymphocytotoxic high-sensitized patients were tested for antibody . The results showed that the positive rate of serum antibody was 20. 6% before the first transplantation, and 75% before retransplantation. Regardlessly in 4℃ or 37℃,all samples from high-sensitized patients reacted to B lymphocyte, but few of them reacted to T lymphocyte.The titer of B lymphocytotoxic antibody from hemodialytic patients with graft loss due to rejection was higher than that from ones whose lymphocyte antibody is caued by blood transfusion or pregnancy.
出处
《中华器官移植杂志》
CAS
CSCD
1995年第3期104-105,共2页
Chinese Journal of Organ Transplantation