摘要
对４０例胃、十二指肠溃疡及胃恶性肿瘤的急性出血病例，在胃镜下局部应用无水酒精及巴特罗酶（ｂａｔｒｏｂｉｎ）作粘膜下注射止血治疗。无水酒精及巴特罗酶治疗各２０例，分别于胃镜下出血点周围粘膜下分点注射。无水酒精每点０；１～０；２ｍｌ，总量０．５～１．２ｍｌ；巴特罗酶每点０．２～０．５ｍｌ（１ｋＵ／２ｍｌ），总量１．０～２；０ｍｌ（０．５～１．０ｋＵ）。除１例喷射性动脉出血外，１次治疗均能有效止血，总有效率为９７．５％。并且再出血率低。其方法简单，止血迅速，副作用小。４０例中除１例局部注射无水酒精后溃疡面积稍有扩大外，其余均无明显的粘膜损伤及坏死，无１例穿孔。但对较粗大的动脉性出血则止血疗效差。由于巴特罗酶首次用于粘膜下局部注射止血，病例数较少，有待临床进一步实践总结。
he authors studied 40 patients with bleeding from peptic ulcer or gastric carcinoma,and evaluated the therapeutic effects of endoscopic injection of absolute alcohol and Bathroxobin,Among them,20 pa- tients were given absolute alcohol and the remaining 20 Bathroxobin(Reptilase).Absolute alcohol was injected submucosally at 4～6pinpoints around the bleeding site(0.1～0.2ml/dose,total dose 0.5～ 1.2ml); Bathroxobin was injected similarly(1 kU/dose,total dose 0.5～1. 0kU).Treatment failed in one patient receiving alcohol because of spouting artery bleeding and surgery was resorted to finally. The other 39 patients had successful stopping of the bleeding in one time,The effective rate is 97.5 per- cent(39/40) and the rate of re- bleeding is low. It is thus shown that endoscopic submucosal injection of absolute alcohol and Bathroxobin for stopping gastric bleeding is safe,simple and effective. However,more experience is needed in this respect.
出处
《中华内科杂志》
CAS
CSCD
北大核心
1995年第7期446-448,共3页
Chinese Journal of Internal Medicine
