摘要
通过对９名男性受试者在分别完成１００－２００ｍ，４００－８００ｍ和１５００－３０００ｍ跑步间歇训练后尿蛋白分子量和等电点的测定发现：①运动时尿液高、低分子量蛋白质排泄率均较运动前明显增加，但以高分子量蛋白质排泄为主；②运动时尿液高、低分子量蛋白质排泄率均以４００－８００ｍ间歇训练时最高，１００－２００ｍ间歇训练时次之，１５００－３０００ｍ间歇训练时最低；③运动时尿液排出的蛋白质以负离子为主，且不同训练后的尿蛋白等电聚焦电泳图谱相似。以上结果提示，人体运动性蛋白尿的直接原因是滤过膜通透性增加和肾小管重吸收减少，而前者变化可能与膜静电屏障减弱有关。
Nine young male
volunteers participated IN three run-training of differnt
intensities(100 200m, 400 800m and 1 500 3000m)at 90% of their
maximum performance. The pre-andpost-training urine samples were
collected to determine the protein molecular weight andisoelectric
point.Quantitative analysis showed that(1) both high and low
molecular weight pro-tein excretion increased significantly, with the
high molecular weight proteins being the dominantcomponent;(2)
excretion rates of both high and low molecular weight urinary
proteins increasedsignificantly after running as compared with
pre-training values, with the values after 400-800mtraining being the
highest and those after 1500-3000m training being the lowest;(3)most
of ex-creted urinary proteins were negative charged and the IEP
patterns were very similar among thethree different training.The
results suggest that increased glomerular fiItration
membranepermeability and impaired tubular protein reabsorption may be
the two direct causes ofexercise-induced proteinuria and the former
factor may has certain relation to the impairedglomerular
electrostatic barrier.
出处
《中国应用生理学杂志》
CAS
CSCD
1995年第4期313-316,共4页
Chinese Journal of Applied Physiology
关键词
运动生理
尿蛋白分子量
尿蛋白等电点
exercise-induced proteinuria
protien
molecular weight
protein isoelectric point
