摘要
本文观察了46例不同证型癫痫患者及25例健康对照者红细胞膜Na^+—K^+—ATP酶活性、血浆MDA含量、SOD活性的检测结果。结果表明,癫痫患者红细胞膜Na^+—K^+—ATP酶活性降低、血浆MDA含量增高、SOD活性降低。异常的程度依次为痰火内闭证>风痰闭阻证>肝肾亏虚证>心脾两虚证。提示癫痫患者有膜ATP酶活性及脂质过氧化损伤;风痰、痰火等不同辨证分型有一定客观指征,对指导中医药临床治疗及探讨病证本质有积极意义。
This article boserved 46 cases of different syndromes and patterns of epilepsy and 25 cases of healthy people, and detected the activity of Na+-K+-ATP enzyme of the RBC membrane, the MDA content in plasma of these two groups. The rusults showed that the activity of Na+-K.+-ATP enzyme of RBC membrane decreased, while the MDA content in plasma increased, and the SOD activity decreased. The degree of anormal succession was : Syndrome of phlegm-fire retention Syndrome of wind-phlegm stagnation Syndrome of deficiency of the liver and kidney Syndrome of deficiency of the heart and spleen. They indkated that the activity of ATP enzyme of RBC membrane decreased and the Lipid peroxide showed damadged in the epiletiics, while different syndromes and patterns of wind-phlegm and phlegm-fire have certain indicators, This research provided the positive significance for guaiding the clinical treatment of TCM and further studying the essence of disease syndromes.
出处
《中国医药学报》
CSCD
北大核心
1995年第5期27-29,共3页
China Journal of Traditional Chinese Medicine and Pharmacy
