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癫痫发作的神经电生理特征 被引量：2

The electrophysiologic character of epileptic seizure
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摘要 Epilepsy is a family of neurological disorders that are common and harmful to human’s health. The etiologies of epilepsy and the clinical manifestations of seizures are complex and various. To elucidate the mechanisms underlying seizure generation, lots of researches in the anatomy, physiology, biochemistry, genetic and molecular biology of epilepsy have been done over many years. However, no single hypothesis provides a unifying framework within which all kinds of epilepsy can be included so far. In fact, the electrophysiologic essence of epileptic seizure is abnormal excess discharges of neurons. On the standpoint of electrophysiology, the reasons of abnormal discharges of neurons are of common character: depolarizing currents with long durations and high amplitudes on cell levels, which is closely related to slow waves with high amplitudes on EEG levels. This can make us understand the mechanism of epileptic seizures better, and is helpful for well control and therapy of seizures. Epilepsy is a family of neurological disorders that are common and harmful to human's health. The etiologies of epilepsy and the clinical manifestations of seizures are complex and various. To elucidate the mechanisms underlying seizure generation, lots of researches in the anatomy, physiology, biochemistry, genetic and molecular biology of epilepsy have been done over many years. However, no single hypothesis provides a unifying framework within which all kinds of epilepsy can be included so far. In fact, the electrophysiologic essence of epileptic seizure is abnormal excess discharges of neurons. On the standpoint of electrophysiology, the reasons of abnormal discharges of neurons are of common character: depolarizing currents with long durations and high amplitudes on cell levels, which is closely related to slow waves with high amplitudes on EEG levels. This can make us understand the mechanism of epileptic seizures better, and is helpful for well control and therapy of seizures.
作者 朱俊玲 蒋大宗
机构地区 第四军医大学神经科学研究所 西安交通大学生物医学工程研究所
出处 《中国病理生理杂志》 CAS CSCD 北大核心 2005年第7期1440-1444,共5页 Chinese Journal of Pathophysiology
关键词 癫痫 发作 电生理学 Epilepsy Seizures Electrophysiology
分类号 R363 [医药卫生—病理学]
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参考文献24

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共引文献15

同被引文献36

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引证文献2

中国病理生理杂志
2005年 第7期

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