摘要
目的:建立腭黏骨膜扩张模型,为腭裂等腭部软组织缺损提供一种新的修复方法。方法:将容量为10ml的软组织扩张器置入4只犬的腭黏骨膜下,同期注入等渗盐水1.0ml,术后第20天再次注水扩张,每次注水1.0～1.5ml,以后每周注水1次,达到预扩张容量后,分别处死动物,进行组织计量学及组织学观察。结果:扩张后的腭黏骨膜组织表现为细胞层数增加,胶原纤维组织增生,血管数量增多。所有标本在组织计量学及组织学上均有“额外”黏骨膜形成。结论:腭黏骨膜扩张术可产生“额外”的黏骨膜,有可能应用于临床腭裂等腭部软组织缺损的修复。
Objective: To establish the model of palatine mucoperiosteal expansion and observe a new possible treatment approach to soft tissue defect of cleft palate. Methods: Expanders of 10ml were implanted beneath the palatine mucoperiosteum in 4 dogs and injected 1.0ml 0.9% NaCl at the same time. 20 days after the placement of the expander, the expander was expanded by 1.0-1.5ml every 7 days again. The dogs were killed after the expanders reached their capacity. All the specimens were performed histomorphometric and histological examinations. Results: Histological results showed the increase in the layer of cell and the number of collagen fibra and blood vessel. All the specimens of expanded tissue showed the formation of extra palatine mucoperiosteal tissue. Conclusion: Expansion technique is able to form extra palatine mucoperiosteal tissue,which could be a new restoration approach to soft tissue defect of cleft palate and others.
出处
《医学研究生学报》
CAS
2005年第7期606-608,i014,共4页
Journal of Medical Postgraduates
关键词
腭黏骨膜
扩张术
腭裂
Palatine mucoperiosteum
Expansion technique
Cleft palate
