摘要
目的观察扩张型心肌病(DCM)患儿心功能不全时血清心肌钙蛋白水平变化,并分析其与预后的关系。方法采用酶联免疫吸附法对56例DCM患儿进行血清心肌肌钙蛋白测定。结果心功能Ⅳ级患儿组血清心肌肌钙蛋白水平(0.53±0.31)μg/L明显高于心功能Ⅲ级组(0.45±0.27)μg/L,而心功能Ⅲ级患儿组明显高于心功能Ⅱ级组(0.29±0.27)μg/L,差异具有显著意义。结论血清心肌肌钙蛋白水平随DCM患儿心功能不全发展渐升高,且与心功能不全程度呈正相关,有助于预后判断。
Objective To observe the serum cardiac troponin I (cTnI) level and to analysis the relations between the serum cTnI level and prognosis in patients with dilated cardiomyopathy (DCM) and Cardiac Dysfunction.Methods Serum cardiac cTnI level was measured by enzyme-linked immunosorbant assay. Results The serum cTnI level in DCM patients with class IV cardiac function (0.53 ±0.31) μg/L was significantly higher than in DCM patients with class Ⅲ cardiac function (0.45±0.27) μg/L.There was significantly difference in serum cTnI levels between DCM patients with class Ⅲ cardiac function and DCM patients with class Ⅱ cardiac function(0.29±0.27) μg/L.Conclusion The higher serum cTnI level is correlated with the severity of cardiac function and may be useful for evaluating prognosis in patients with DCM.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2005年第7期637-638,共2页
Journal of Applied Clinical Pediatrics
关键词
心肌病
扩张型
儿童
肌钙蛋白
dilated cardiomyopathy
children
Cardiac troponin I
