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火把花根治疗IgA肾病的研究 被引量:8

Study of Colquhounia root on IgA nephropathy
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摘要 目的比较西医常规疗法和火把花根联合西医常规疗法治疗IgA肾病的临床疗效,探讨火把花根在IgA肾病治疗中的作用。方法将72例患者按31随机分为治疗组和对照组。2组均用西医常规治疗,治疗组在此基础上加用火把花根,疗程2个月。观察2组临床疗效及尿分析、肾功能、血清免疫球蛋白等变化。结果治疗组总有效率91%,对照组67%,2组比较有统计学差异(P<0.05)。治疗组在减少24h尿蛋白定量和尿RBC计数方面优于对照组,有统计学差异(P<0.01或0.001)。2组治疗后血清免疫球蛋白仅治疗组IgA下降(P<0.01)。结论火把花根治疗IgA肾病有效,并具有免疫抑制作用,疗效明显优于单纯西医疗法。 Objective It is to compare the clinical curative effect of western medicine normal treatment and Colquhounia root combined with western medicine normal treatment on IgA nephropathy and to discuss the function of Colquhounia root on the treatment of IgA nephropathy. Methods 72 patients were divided into treatment group and control group with the proportion of 3:1. Both groups were given western medicine normal treatment. The treatment group was added Colquhounia root. The course of treatment was two months. The clinical curative effect and the changes of urine analysis, renal function and serum immunoglobulin were observed. Results The total effective rate of treatment group was 91% and that of control group was 67%. There was significant difference between the two groups (P<0.05). The effect of decreasing urinary protein quantitation per 24h and quantity of urinary RBC in treatment group was better than that in control group. The difference was significant (P<0.01 or 0.001). The content of serum immunoglobulin didn't decrease in both groups after treatment except IgA in treatment group (P<0.01). Conclusion Colquhounia root has a better curative effect on IgA nephropathy than simple western treatment and has an immunizing inhibition function.
出处 《现代中西医结合杂志》 CAS 2005年第14期1819-1820,共2页 Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词 IGA肾病 火把花根 肾功能 IgA nephropathy Colquhounia root renal function
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