摘要
阻塞豚鼠内淋巴管及内淋巴囊造成实验性膜迷路积水动物模型，分别观察积水后１、２、３个月耳蜗第三回外侧壁微循环改变，测定螺旋韧带血管（ＳＬＶ）及血管纹血管（ＳＶＶ）的管径及流速。发现积水三个阶段中，ＳＬＶ管径平均缩小０．８０μｍ、０．８７μｍ、１．２１μｍ（Ｐ＜０．０５），流速分别下降１００．８μｍ／ｓ、１４１．０μｍ／ｓ、１３６．０μｍ／ｓ（Ｐ＜０．０５）。ＳＶＶ管径至积水３个月扩张才有显著性，平均扩张０．９３μｍ，但ＳＶＶ管径有随积水时间延长而扩张增大趋势（Ｐ＜０．０５）。ＳＶＶ流速与对照耳比虽都有下降，但无统计学差异（Ｐ＜０．０５）。表明膜迷路积水后ＳＬＶ及ＳＶＶ均受影响，ＳＬＶ变化明显。对引起这种变化的机理进行了探讨。
guinea pigs were made as a modle of endolymphatic hydrops by obliteration of en-dolymphatic sac and duct.Cochlear microcirculation of the lateral wall in the third turn was observed and recorded.The diametes and velocities of the vessels were analysed in IBAS image system.The stria vascular vessels and spiral ligament vessels were analysed repectively.The data showed : 1.1,2 and 3 months after operation, the diameter of SLV averaely decreased 0. 80μm,0.87μm,1. 21μm(P <0. 05) respectively and velocity decreased 100.8μm/s,141.0μm/s, 136.0μm/ls (P<0.05 ) repec-tivly;2.The diameter of SVV dilated 3 months after operation. With the elapse of time,SVV had a dilation tendency. These indicated that hydrops effect different changes in SLV and SVV. The over-pressure of endolymphatic fluid may be the possible cause of changes in SVV and SLV.
出处
《中华耳鼻咽喉科杂志》
CSCD
1994年第5期259-262,T054,共5页
Chinese Journal of Otorhinolaryngology
