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豚鼠外淋巴间隙阻断术对前庭和耳蜗的影响 被引量:1

The Influence of Obliteration of External Lymphatic Space on the Vestibule and the Cocblea in Guinea Pigs
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摘要 对18只白色豚鼠施行单侧外半规管外淋巴间隙阻断术。术前、后观察ABR、旋转试验,并作火棉胶连续切片光镜检查。结果提示:手术前、后ABR阈值经统计学处理差异无显著性,而限震持续时间差异有显著性(术后缩短),初步表明本手术可致豚鼠前庭功能降低而未明显损伤耳蜗功能。 Obliteration of the external lymphatic space on 18 guinea pigs was performed.The lymphatic space of the horizontal semicircular canal was blocked by fascia, Auditory(ABR) and vestibular functions were tested before and after the surgical obliteration。Morphologic changes in the cochlea and vestibule were observed under light microscope. It was found that there was no significant difference in the threshold of ABR before and after the operation However,the sustained time of nystagmus was significantly decreased after the operation,Our results indicate that this surgical proce-dure may damage vestibular function,but produce no evident damage to the cochlear function.
出处 《中华耳鼻咽喉科杂志》 CSCD 1994年第2期96-97,T014,共3页 Chinese Journal of Otorhinolaryngology
关键词 半规管 外科手术 听力 诱发电位 Semicircular canals Surgery Audiometry,evoked response
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参考文献2

  • 1李新吾,临床耳鼻咽喉科杂志,1987年,1卷,6页
  • 2范家裕,国外医学耳鼻咽喉科学分册,1981年,5卷,5期,341页

同被引文献15

  • 1林枫,王跃建,虞幼军,刘振,刘秋玲.后半规管阻塞术治疗难治性位置性眩晕的远期疗效[J].中国校医,2005,19(2):187-188. 被引量:2
  • 2吴雅琴,殷善开,时海波,周慧群,倪凌达.半规管阻塞技术治疗迷路瘘管初步报告[J].上海交通大学学报(医学版),2007,27(9):1056-1057. 被引量:5
  • 3Pames LS, McClure JA. Effect on brainstem auditory evoked responses of posterior semicircular canal occlusion in guinea pigs [J]. J Otolaryngol, 1985, 14(3) :145-150.
  • 4Parnes LS, McClure JA. Posterior semicircular canal occlusion for intractable benign paroxysmal positional vertigo [ J ]. Ann Otol Rhinol Laryngol, 1990, 99(5 Pt 1 ) :330-334.
  • 5Pames LS, MeC|ure JA. Posterior semicircular canal occlusion in the normal hearing ear[J]. Otolaryngol Head Neck Snrg, 1991, 104(1) :52-57.
  • 6Yin S, Chen Z, Yu D, et al. Triple semicircular canal occlusion for the treatment of MOnire' s disease [ J ] . Acta Otolaryngol, 2008, 128(7): 739-743.
  • 7Nomura Y, Kobayashi H. Laser irradiation of the semicircular canal: occlusion of the canal or duct [J]. Acta Otolaryngol, 2012, 132(1) :106-111.
  • 8Beyea JA, Agrawal SK, Parnes LS. Transmastoid semicircular canal occlusion: a safe and highly effective treatment for benign paroxysmal positional vertigo and superior canal dehiscence [ J ]. Laryngoscope, 2012, 122 (8) : 1862-1866.
  • 9Ahmed RM, Pohl DV, MacDougall HG, et al. Posterior semicircular canal occlusion for intractable benign positional vertigo: outcome in 55 ears in 53 patients operated upon over 20 years[J]. J Laryngol Otol, 2012, 126(7) : 677-682.
  • 10Ramakrishna J, Goebel JA, Parnes LS. Efficacy and safety of bilateral posterior canal occlusion in patients with refractory benign paroxysmal positional vertigo: case report series ] . Otol Neurotol, 2012, 33(4): 640-642.

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