摘要
应用抗CD56单克隆抗体和ABC技术观察了54例颅内肿瘤细胞的CD56表达状况。34例胶质瘤中31例(91.2％)阳性,其中包括小脑髓母细胞瘤2例,大脑PNET1例。10例脑膜瘤中3例阳性,原发性恶性淋巴瘤2例均阳性。胚生殖细胞瘤1例、转移癌7例均阴性。本组结果表明CD56并非神经鞘细胞、少突胶质细胞及其肿瘤的特异性标记物。但可作为颅内原发性肿瘤,特别是胶质瘤与转移癌鉴别的重要参考指标。
Fifty four intracranial tumors were observed by anti-CD56 monoclonal antibody and ABC immunohistochemical technique. Thirty one (91.2%) of 34 gliomas were positive for CD56 and there were one cerebral PNET and two medulloblastomas in these positive gliomas. Three of 10 meningiomas and two primitive malignant lymphomas expressed CD56, too. A germi-
noma and seven metastatic carcinomas were negative for CD56. The results suggest that CD56 may not be the specific marker of neurinoma and oligodendroglioma but may be regarded as important referential basis differentiating almost all gliomas from metastatic carcinomas.
出处
《临床与实验病理学杂志》
CAS
CSCD
北大核心
1994年第4期276-278,T004,共4页
Chinese Journal of Clinical and Experimental Pathology
