摘要
目的探讨肺部念珠菌感染的易患因素及预后影响因素。方法应用回顾性调查的方法对187例肺部念珠菌感染的患者进行分析。结果肺部念珠菌感染的风险因子中长期使用糖皮质激素、免疫抑制剂,以及慢性肾脏疾病、白血病有统计学意义;广谱抗生素3～14天后使用抗真菌药物与广谱抗生素15～28天后使用抗真菌药物相比,可显著降低肺部真菌感染的死亡率。结论合理使用抗菌药物及糖皮质激素、免疫抑制剂以及及时早期诊断和抗真菌治疗是降低呼吸道念珠菌感染并降低死亡率的重要措施。
Objective To find out the clinical features, therapeutic outcome, prognosis and the major predisposing disease of pulmonary candidosis. Methods 187 cases with pulmonary candidosis were retrospectively analyzed. Results The risk factors for pulmonary candidosis were related to the treatments with broad spectrum cortical hormone and immunosuppresssive agent. The patients with chronic basic diseasese were susceptible to pulmonary candidosis. There was a Significant difference for the mortality of pulmonary candidosis between the group of using antifungal drug after using broad spectrum antibacterial for 3～14 days and for 15～28 days. Conclusion Reasonable use of antibacterial and cortical hormone and immunosuppressive agent as well as early diagnosis and treating fungus infection would be important measures for decreasing the morbidity and the mortality of pulmonary candidosis.
出处
《广州医药》
2005年第4期31-33,共3页
Guangzhou Medical Journal
