摘要
上腹部器官簇移植受者5例,其中男性4例,女性1例;胰腺癌肝转移3例,肝癌胰腺及腹腔淋巴结转移2例.5例患者分别于2004年5月至2005年4月接受上腹部器官簇移植治疗,切除脏器包括全胃、肝脏、胰腺、脾脏、十二指肠及部分空肠, 移植器官簇包括肝脏、胰腺、十二指肠及部分空肠.所有患者均于术后4～6 h清醒,8～14 h撤除呼吸机;术后第3～7 d从SICU转回普通病房开始康复治疗.AST、ALT及TB等肝功能指标在术后1周趋于正常水平;C-肽、血淀粉酶、血清胰岛素水平在1～2周内达到正常范围.目前,除1例患者出现肿瘤复发外,其余病例一般情况良好.肝胰十二指肠器官簇移植具有肿瘤根治彻底、器官功能替代全面的特点,是上腹部多脏器恶性肿瘤的有效治疗方法.
Five patients underwent abdominal multivisceral transplantation from May 2004 to April 2005, including 4 males and 1 female, 3 cases of hepatic metastesis from pancreatic cancer, 2 cases of liver cancer with pancreatic and peritoneal lymphatic metastasis. Removed organ included stomach, liver, pancreas, spleen, duodenum and jejunal loop, transplanted organ included liver, pancreas, duodenum and jejunal loop. All patients restored consciousness within 4～6 hours postoperatively, and discharged of respirator within 8～14 hours. Recovering remedy initiated on 3～7 d postoperatively as tranfered out of SICU. AST, ACT and TB decreased to normal level 1 week postoperatively, C-tide, blood Amylase concertration, blood insuline concertration resumed to normal range 1～2 weeks postoperatively. All cases recovered well except 1 case of tumor recurrence with follow-up to date. Abdominal organ cluster transplantation could be an effective therapeutic approach for muctiple organ malignance offering potential curative result.
出处
《中国现代手术学杂志》
2005年第2期95-97,共3页
Chinese Journal of Modern Operative Surgery
基金
广东省自然科学基金 (21899)
广东省"千百十"工程基金(Q02033)
广东省科委攻关基金(99M04902C)
