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弥散加权成像及氢质子磁共振波谱在新生儿缺氧缺血性脑病诊断中的应用 被引量：2

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摘要 围产期窒息而导致的新生儿缺氧缺血性脑病(HIE)是造成儿童永久性神经功能障碍的主要原因之一。磁共振弥散加权成像及磁共振波谱分析分别利用水分子的限制性弥散及化学位移和J耦合原理,无创性地研究脑内组织生理生化及代谢改变,为进一步明确HIE的发病机理及早期准确的评估预后提供了有效的手段和方法。
作者 程凤燕 刘国瑞
机构地区 汕头大学医学院第二附属医院放射科
出处 《汕头大学医学院学报》 2005年第2期121-123,共3页 Journal of Shantou University Medical College
关键词 新生儿缺氧缺血性脑病 氢质子磁共振波谱 磁共振弥散加权成像 磁共振波谱分析 诊断 神经功能障碍 围产期窒息 耦合原理 化学位移 代谢改变 生理生化 评估预后 发病机理 永久性 限制性 水分子 无创性 HIE
分类号 R722.12 [医药卫生—儿科] R742.1 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献21

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  • 7郭岳霖 刘国瑞.急性期重度新生猪缺氧缺血性脑病模型的磁共振弥散加权与病理对照研究[C]..见:全军第十届影像学术大会论文汇编[C].广州,2004.729-730.
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二级参考文献21

  • 1韩玉昆 虞人杰.新生儿缺氧缺血性脑病临床诊断依据和分度[J].中华儿科杂志,1990,28:31-31.
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共引文献23

同被引文献25

  • 1朱文珍,漆剑频,王承缘,夏黎明,常立文,胡军武,冯定义,邹明丽,曾引华.新生儿缺氧缺血性脑病的MR波谱研究[J].中华放射学杂志,2006,40(10):1042-1046. 被引量：10
  • 2Wang C J, McGlynn EA, Brook RH, et al. Quality-of-care indicators for the neurodevelopmental follow-uD of very low birth weight cMldren : Re- suits of all expert panel process. Pediatrics ,2006,117:2080-2092.
  • 3Fan G,Wu Z,Chen L,et al. Hypoxia-ischemiec encephMopathy in full- term neonate : Correlation proton MR spectroscopy with MR imaging. Eur J Radio1,2003 ,45 :91-98.
  • 4Hüppi P S,Lazeyras F.Proton magnetic resonance spectroscopy ((1)H-MRS) in neonatal brain injury. Pediatric Research . 2001
  • 5Abdulhakim ?oskun,Maarten Lequin,Mark Segal,Daniel B. Vigneron,Donna M. Ferriero,A. James Barkovi.Quantitative Analysis of MR Images in Asphyxiated Neonates: Correlation with Neurodevelopmental Outcome. AJNR Am. J. Neuroradiol . 2001
  • 6Kadota T,Horinouchi T,Kuroda C.Development and aging of the cerebrum: assessment with proton MR spectroscopy. American Journal of Neuroradiology . 2001
  • 7Robertson N J,Lewis R H,Cowan F M,Allsop J M,Counsell S J,Edwards A D,Cox I J.Early increases in brain myo-inositol measured by proton magnetic resonance spectroscopy in term infants with neonatal encephalopathy. Pediatric Research . 2001
  • 8Ancora G,Testa S,Grandi C,et al.Prognostic value of brain proton MR spectroscopy and diffusion tensor imaging in newborns with hypoxic-ischemic encephalopathy treated by brain cooling. Neuroradiology . 2013
  • 9Lee Byong Sop,Woo Chul-Woong,Kim Sang-Tae,Kim Ki-Soo.Long-term neuroprotective effect of postischemic hypothermia in a neonatal rat model of severe hypoxic ischemic encephalopathy: a comparative study on the duration and depth of hypothermia. Pediatric Research . 2010
  • 10Guoguang Fan,Zhenhua Wu,Liying Chen,Qiyong Guo,Binbin Ye,Jian Mao.??Hypoxia-ischemic encephalopathy in full-term neonate: correlation proton MR spectroscopy with MR imaging(J)European Journal of Radiology . 2002 (2)

引证文献2

二级引证文献6

汕头大学医学院学报
2005年 第2期

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