摘要
本文分析了８７例鼻咽癌患者放疗后１～１５年，有４０例出现不同程度颈部纤维化改变，占４６％。其中轻度２６例（２９．９％），中度１２例（１３．８％）重度２例（２．３％）。应用Ｃ０（６０）γ线及８ＭｖＸ线纤维化发生率分别为３５．１％，４１．６％，而应用γ线＋１２０～１４０ｂｙＸ线，γ线＋１０～１４Ｍｅｖβ束均为８３．３％，放射剂量是影响纤维化的最重要因素之一，＜８００ＭＧ，，７０例中２７例出现纤维化，占３８．６％，≥８０００ＣＧｙ，１７例中１３例出现纤维化，占７６．５％（Ｐ＜０．０１）。对颈部淋巴结给一定剂量后估计难以消失的，不应盲目加量。
NPC patients 1 - 15 years after their radiotherapy which led to nab fibrosis in 40 patientswere analysed. When 60C0-γray or 8Mv X-ray was delivered, the incidence of fibrosis was only35. 1 %, 41. 6 %, respeCtively, while γ-ray combined with 120～ 140Kv X -ray or 10-14Mev β raygiven, the incidence rose to 83. 3%. The results shewed the most important cause of fibrosis was thetumor dose. When it was<800cGY, only 27 of 70 patients (38. 6%) developed fibrosis, when≥8000cGY, 13 of 17 causes (76. 5 % ) mauifersed neck fibrosis, (P<0. 01 ). Futher radioation shouldnot be given blindly after fairly high dose to neck nodes which were dsthated not to be eliminatedby radiotheray.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
1994年第5期331-332,共2页
Cancer Research on Prevention and Treatment
