摘要
作为生物材料的组织工程支架,其物理机械性能的改善成为生物医学的热点研究课题,具有良好的生物活性及生物相容性的磷酸钙陶瓷纤维在生物材料的增强领域有着广泛的需求。本实验首先用溶胶-凝胶体系制备出磷酸钙陶瓷纤维的初始浆料,根据蚕丝纤维的物理化学性质,预先对丝纤维表面进行裂纹化和浆料吸附增强的处理,探讨了凝胶浆料的组分与丝纤维化学性质的相互配伍方式,使凝胶浆料中的羟基磷灰石粉粒以丝纤维作导向载体在其轴向实现紧密有序的排列,制定出陶瓷纤维初坯的晶化烧结工艺,最终制备出具有生物活性的磷酸钙陶瓷短纤维。
Improving mechanical properties of tissue engineering scaffolds as biomaterial has been focus in field of biomedical application.Calcium phosphate ceramic fiber (CPCF) with perfectible bioactivity and compatibility has widely demands on the kingdom of reinforcing biomaterials.Firstly,the primary slurry was prepared for producing CPCF by using sol-gel system in this study.In advance,silk fiber was treated for making little crack on its surface and reinforcing (adsorption) of the slurry according to the physical and chemical properties of silk proteins, the relative matching mode (between) the component of ceramic slurry and the chemical properties of silk was analyzed. Hydroxyapatite (HA) powders has been arranged on axis of silk as oriented usher with compactness and sequence. The sintering process for crystallization of original ceramic fibrous model was made and finally the bioactive CPCF was prepared.
出处
《苏州大学学报（工科版）》
CAS
2005年第2期32-34,52,共4页
Journal of Soochow University Engineering Science Edition (Bimonthly)
