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低蛋白饮食配合α-酮酸延缓老年慢性肾脏病进展的临床观察 被引量:1

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摘要 目的探讨低蛋白饮食配合α-酮酸在改善老年慢性肾脏病(CKD)患者营养状态、延缓病情进展中的作用。方法40例老年CKD患者肾小球滤过率(GFR)30-50ml/min,按年龄尾数的奇偶性分为干预组和对照组。干预组给予低蛋白饮食(0.6g·kg^-1·d^-1)配合α-酮酸(口服开同,0.1g·kg^-1·d^-1);对照组给予既往医生推荐的低蛋白饮食(0.8~1.0g·kg^-1·d^-1)。随访1年,比较两组的营养状态及肾功能变化。结果干预组血清白蛋白、转铁蛋白等营养指标明显高于对照组(P<0.05);GFR下降速度明显低于对照组(P<0.05)。结论低蛋白饮食配合α-酮酸治疗老年CKD可以有效减缓肾衰竭的进展,明显改善患者的营养状况。
出处 《临床肾脏病杂志》 2005年第3期109-111,共3页 Journal Of Clinical Nephrology
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