摘要
报告１０３例肺癌病人血清促肾上腺皮质激素原氨基端肽（以上简称Ｎ－ＰＯＭＣ）水平，超高限为５０．５％，其中鳞癌超高限为５２．２％、腺癌５０％、小细胞癌４７．３％、未能分型的肺癌５７．１％。小细胞肺癌Ⅲｂ、Ⅳ期１８例中１１例超高限，９例Ⅱ－Ⅲａ病人中３例超高限。本组病人无柯兴氏综合征表现。另报告类癌８例、胸腺瘤及神经纤维瘤各１例，血清Ｎ－ＰＯＭＣ均明显增高，其中６例有柯兴氏综合征表现。综上所述血清Ｎ－ＰＯＭＣ值测定能否作为肺癌的早期诊断、预后及复发的指标之一值得进一步探讨。
Abstract Serum N-POMC level of 103 cases of lung cancer were measured in our
hospital.The results were as follows:The lung cancer group,50.5%,of patienst has an N-PONC
level above the nor-mal upper limit.The percentages of the N-POMC levels above the normal
limit in lung cancers,such as:squamous-cell carcinoma, adenocarcinoma,SCLC and
undifferentiated carcinoma were52.2%, 50.0%,47.3% and 57.1%,respectively. There was no
statistically significant difference ofN-POMC levels among these kinds of lung cancers, Eleven
of 18 cases of SCLC patients in stageⅢb or Ⅳ,and 3 of 9 cases of SCLC patients in stage Ⅲa
had N-POMC levels above theupper normal limit. Could serum N- POMC be one of the indexes
for assisting the diagnosis andprognosis of lung cancer needs further investigation.Cases with
carcinoid,thymoma and neurofibroma had higher N-POMC levels too. Six pateintshad Cushing
syndrome.
出处
《中华肿瘤杂志》
CAS
CSCD
北大核心
1994年第4期291-294,共4页
Chinese Journal of Oncology
