摘要
目的观察丙种球蛋白联合阿司匹林在预防川畸病发生冠状动脉病变的作用。方法对26例确诊为川畸病患者早期给予丙种球蛋白联合阿司匹林进行综合预防治疗。结果26例中出现冠状动脉病变4例,发生率仅为15.38%。随访19例半年～5年无复发,其中4例冠状动脉病变者有所恢复。结论早期使用丙种球蛋白和阿斯匹林可降低川畸病冠状动脉病变的发生率;而肾上腺皮质激素并不能改善川畸病的临床症状。
Objective To study the efficacy of gamma globulin in combinat ion with aspirin for prevention of coronary disease induced by Kawasaki disease. Methods 26 patients proven with Kawasaki disea se were given early preventive treatment with gamma globulin in combination with aspirin. Results In 26 treated cases, 4 were f ound with coronary disease, the incidence rat e was 15.38%. No recurrence were found in the 0.5～5 year follow up for 19 cases . Symptoms in 4 of the patients with coronary disease improved. Conclusion Gamma globulin in combination with aspirin in ea rly treatment of Kawasaki d isease can reduce the incidence rate of coronary disease; and adrenal cortex hor mone is ineffective for treatment of Kawasaki disease.
出处
《右江民族医学院学报》
2005年第3期303-305,共3页
Journal of Youjiang Medical University for Nationalities
