摘要
目的探讨凋亡相关基因TFAR19(TF-1cellapoptosis-relatedgene19)在风湿性关节炎(RA)检测中的应用价值,分析其与RA病情的关系。方法用ELISA法分别测定39例活动期RA(活动期组)、31例稳定期RA(稳定期组)的TFAR19抗体水平,设20例健康人为对照组。结果活动期组血清中TFAR19抗体水平高于稳定期组和对照组(t分别为8.24,8.36,P均<0.01);活动期组血清TFAR19检测阳性率明显高于稳定期组和对照组(P均<0.01)。结论TFAR19与RA发病、病情有密切关系。
Objective To investigate the va lue of determination of TFAR_(19) (TF-1 cell apoptosis-related gene 19) in diagnosis of rheumatoid arthritis (RA) and analyze its relationship with the progression of RA. Method s An ELISA technique was used to detect TFAR_(19) antibody levels in 39 patients with a ctive phase RA (the active phase group) and in 31 patients with stationary phase RA (the stationary phase group). 20 healthy individuals were chosen in the cont rol group. Results In active phase group, serum TFAR_(19) levels were higher than those in the stationary group and the control group (t=8.24 and 8.3 6, respectively, all P<0.01); the positive detectable rate of TFAR_(19) w as also higher than those in the stationary group and the control group (all P <0.01). Conclusion TFAR_(19) is closely re lated to the progression of RA.
出处
《右江民族医学院学报》
2005年第3期292-294,共3页
Journal of Youjiang Medical University for Nationalities
