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QT间期相关基因研究进展

Research progress of Q-T interval-associated genes
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作者 丁秀原 米杰
机构地区 首都儿科研究所流行病学研究室
出处 《中国药物与临床》 CAS 2005年第6期405-408,共4页 Chinese Remedies & Clinics
基金 国家自然科学基金资助项目(30371238)
关键词 基因研究进展 相关 校正QT间期 心电图波形 QTC间期 心脏除极 临床工作 心脏疾病 心室除极 收缩时间 QRS波 正常值 复极 心率
分类号 R540.41 [医药卫生—心血管疾病]
  • 相关文献

参考文献29

  • 1梁黔生,陆再英.QT离散度不能反映心肌复极的区域性差异[J].中华心血管病杂志,2003,31(7):498-501. 被引量：6
  • 2洪昭光,程秀琴.心脏性猝死（2）[J].中国循环杂志,1995,10(4):193-194. 被引量：18
  • 3Keating MT,Atkinson D,Dunn C,et al. Linkage of a cardiac arrhythmias,the long QT syndrome and the Harvey ras-1 gene.Science, 1991,252: 704-706.
  • 4Jiang C,Atkinson D,Towbin JA,et al.Two long QT syndrome loci map to chromosome 3 and 7 with evidence for further heterogeneity. Nature Genet, 1994,8:141-147.
  • 5Schott J, Charpentier F, Peltier S, et al.Mapping of a gene for long QT syndrome to chromosome 4q25-27.Am J Hum Genet, 1995,57:1114-1122.
  • 6Splawski I,Tristani-Firouzi M,Lehmann MH,et al. Mutations in the minK gene cause long QT syndrome and suppress Iks function. Nature Genet, 1997,17: 338-340.
  • 7Abbott GW,Sesti F,Splawski I,et al. MiRPI forms Ikr potassium channels with HERG and is associated with cardiac arrhythmia.Cell, 1999,97:175-187.
  • 8Moss AJ.Long QT Syndrome .JAMA,2003,289(16) :2041-2044.
  • 9Li GR,Feng JL,Xue LX,et al.Evidence for two components of delayed rectifier K+ current in human ventricular myocytes. Circ Res, 1996,78: 689-696.
  • 10Tristani-Fironzi M,Chen J,Mitcheson JS,et al. Molecular biology of K+ channels and their role in cardiac arrtythmias. Am J Med,2001,110: 50-59.

二级参考文献14

  • 1Satler CA,Walsh EP,Vesely MR,et al. Novel missense mutation in the cyclic nucleotide-binding domain of HERG causes long QT syndrome. Am J Med Genet, 1996,65:27-35.
  • 2Pietila E,Fodstad H,Niskasaari E,et al.Association between HERG K897T polymorphism and QT interval in middle-aged Finnish women.J Am Coll Cardiol,2002,40:511-514.
  • 3Mi J,Law CM,Zhang KL,et al.Effects of infant birthweight and maternal body mass index in pregnancy on components of the insulin resistance syndrome in Chin a. Ann Intern Med, 2000,132:253-260.
  • 4Higham PD,Camplell RWF.QT dispersion. Br Heart J,1994,71:508-510.
  • 5Chiang CE,Roden DM.The long QT syndromes:genetic basis and clinical implication.J Am Coll Cardiol, 2000,36:1-12.
  • 6Splawski I,Shen JX,Timothy KW,et al. Spectrum of mutations in long-QT syndrome genes KVLQT1,HERG,SCN5A,KCNE1 and KCNE2.Circulation, 2000,102:1178-1185.
  • 7Curran ME,Splawski I,Timothy KW,et al.A molecular basis for cardiac arrhythmia:HERG mutations cause long QT syndrome. Cell,1995,80: 795-803.
  • 8Davey P.QT interval and mortality from coronary disease. Prog Cardiovasc Dis, 2000,43: 359-384.
  • 9Wollnik B,Schroeder BC,Kubisch C,et al. Pathophysiological mechanisms of dominant and recessive KVLQT1 channel mutations found in inherited cardiac arrhythmias. Hum Mol Genet, 1997,6:1943-1949.
  • 10Sanguinetti MC.Long QT syndrome:ionic basis and arrhythmia mechanism in long QT syndrome type 1.J Cardiovasc Electrophysiol,2000,11:710-712.

共引文献21

中国药物与临床
2005年 第6期

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