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心肌病猝死高危因素初步分析 被引量:6

Risk factor stratification of sudden death in idiopathic cardiomyopathy
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摘要 178例原发性心肌病及19例猝死分析表明:(1)持续性室性心动过速(室速)者猝死率55.2%(16/29),非持续性室速者猝死率5.4%(3/56);(2)心室程序刺激诱发持续性室速阳性者猝死率52.6%(10/19),诱发阴性者猝死率10%(2/20);(3)心室晚电位(VLP)阳性者猝死率53.3%(8/15),VLP阴性者猝死率11.1%(2/8);(4)扩张型心肌病(DCM)测量猝死者生前右室流出道平均3.76±0.19cm,明显大于DCM存活者(平均2.94±0.29cm)。可见自发和诱发持续性室速、VLP阳性、右室流出道扩张等均提示心肌病猝死高危因素。 Abstract In 178 patients with idopathic cardiomyopathy , the risk factor stratifications of sudden death (SD) were analysed. Among them, 19 cases died suddenly.55. 2% (16/29) of patients with SD had a history of recurrent sustained ventricular tachycardia (S-VT). The incidence of SD in the patients with recurrent non-sustained ventricular tachycardia (nonS-VT) was 5. 36% (3/56). Programmed electrical stimulation (PES) was performed in 39 patients with ventricular tachyarrhythmias (VT), 19 patients had inducible S-VT, SD occured in 10 patients (52. 6%). S-VTs were not induced in 20 patients, SD occured in only 2 patients (10%) . Signal-averaged ECG (SAECG) was studied in 33 patients with VT. The late potenitials (LPs) were demonstrated in 15 cases, in which 8 cases suffered SD (53. 3%). The SAECG was normal in 18 cases , SD occured in only 3 cases (16. 6%). The right ventricular out-flow tract studied by echocardiogram was greater in SD group than in non-SD group. This study has demonstrated that S-VT occured spontaneouly or induced by PES, positive LPs and RV dilation may predict the risk to arrhythmogenic SD in patients with idiopathic cardiomyopathy.
出处 《中华心血管病杂志》 CAS CSCD 北大核心 1994年第5期363-365,共3页 Chinese Journal of Cardiology
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