摘要
Hyperlipemia rabbit models established with high cholesterol and fat diet were treated with direct moxibustion and medicinal cake-separated moxibustion. The post-treatment plasma 6-keto-prostaglandin F1α (6-keto-PGF1α) and thromboxane B2 (TXB2) contents were determined by radioimmunoassay. Results indicated that the plasma 6-keto-PGF1α content significantly increased, the TXB2 level decreased (P＜0.05)and the TXB2 /6-keto-PGF1α ratio also decreased (P＜0.01) in the medicinal cake-separated moxibustion group as compared with those in the model group respectively, but there was no significant difference between the medicinal cake-separated moxibustion group and the direct moxibustion group (P＞0.05),suggesting that both the medicinal cake-separated moxibustion and direct moxibustion can regulate the plasma 6-keto-PGF1α and TXB2 contents, and the TXB2/6-keto-PGF1α ratio with similar actions, and have a certain protective action on endothelial cells of the aorta in the rabbit of hyperlipemia.
Hyperlipemia rabbit models established with high cholesterol and fat diet were treated vith direct moxibustion and medicinal cake-separated moxibustion. The post-treatment plasma 6-keto-prostaglandin F_(1α) (6-keto-PGF_(1α)) and thromboxane B2 (TXB_2) contents were determined by radioimmunoassay. Results indicated that the plasma 6-keto-PGF_(1α) content significantly increased,the TXB_2 level decreased (P<0.05) and the TXB_2 /6-keto-PGF_(1α) ratio also decreased (P<0.01) in the medicinal cake-separated moxibustion group as compared with those in the model group respectively,but there was no significant difference between the medicinal cake-separated moxibustion group and the direct moxibustion group (P>0.05), suggesting that both the medicinal cake-separated moxibustion and direct moxibustion can regulate the plasma 6-keto-PGF_(1α) and TXB_2 contents,and the TXB_2/6-keto-PGF_(1α) ratio with similar actions,and have a certain protective action on endothelial cells of the aorta in the rabbit of hyperlipemia
