摘要
将自制多孔磷酸三钙陶瓷人工骨与人红骨髓细胞体外混合培养，４周时，大量骨髓细胞贴附于陶瓷表面、孔道内壁及培养孔底。将陶瓷材料与红骨髓作自体复合移植于兔股四头肌肉，４周时，植入陶瓷表面及孔道内有大量新生骨及骨髓形成。结果显示该陶瓷人工骨与骨髓有良好生物相容性，两者复合移植具有良好成骨作用。本文还探讨了复合移植的成骨机理及临床意义。
Following the culture of human red marrow with porous TCP ceramics in vitro,a large amount culturing marrow cells adhered well to the surface and inner wall of TCP ceramics and spread well over the dish bottom after 4 weeks cultivation. Following the compound transplantation of porous TCP ceramics with red marrow into quadriceps femoris muscle of rabbites, a huge amount of new bone and marrow formed in these sites on and in the ceramics after 4 weeks transplantation. These results showed an excellent biocompatibility between TCP ceramics and marrow and an excel- lent osteogenic effect in the compound transplantation. The mechanism of ossification and clinical significance about compound transplantation had been discussed in this article.
出处
《中华实验外科杂志》
CAS
CSCD
北大核心
1994年第5期263-264,共2页
Chinese Journal of Experimental Surgery
