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罂粟碱开放血脑屏障后化学治疗大脑恶性胶质瘤 被引量:7

Chemotherapy of the malignant cerebral glioma after opening blood-brain-barrter by papavering
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摘要 本文报告96例大脑恶性胶质瘤术后经颈动脉注入罂粟碱开放血脑屏障后注入BCNU治疗,而后放疗,放疗后再行化疗。96例平均生存期101.7周,中位生存期106周,仍有36例生存。作者认为罂粟碱开放血脑屏障后化疗简单、安全及有效,且病人痛苦少,费用低,乐于主动接受多次化疗。 Abstract Ninety-six postoperitive malignant cerebral gliomas were treated by intracarotid infusion of papaverine for opening the blood-brain-barrier,and follow by intracarotid infusion of BCNU radiotherapy and the chemotherapy were also used after ward. The mean survial time was 101. 7 weeks with 106 weeks of median survival time in the all patients. Thirty-six patients still living. We considered combination of papaverine and BCNU infusion for treatment of malignant cerebral glioma is simple,sefe and effective.
出处 《中华神经外科杂志》 CSCD 北大核心 1994年第6期339-340,共2页 Chinese Journal of Neurosurgery
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参考文献4

  • 1薛洪利,中华神经外科杂志,1993年,9卷,267页
  • 2李明伟,中华神经外科杂志,1992年,8卷,14页
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同被引文献18

  • 1薛洪利,王翚,孔令权,董宝印,冯艳华.罂粟碱开放血脑屏障与卡氮芥治疗恶性胶质瘤的研究[J].解放军医学杂志,1993,18(5):363-366. 被引量:3
  • 2刘启德,梁美蓉,陈芝喜,冯美蓉,赵萍.冰片对庆大霉素透血脑屏障的影响[J].广州中医学院学报,1994,11(1):37-40. 被引量:105
  • 3王宁生,梁美蓉,刘启德,叶少梅.冰片“佐使则有功”之实验研究[J].中医杂志,1994,35(1):46-47. 被引量:84
  • 4刘英华,王忠诚,石祥恩,张懋植.恶性胶质瘤施行嘧啶亚硝脲化学治疗临床观察[J].中华神经外科杂志,1997,13(1):28-30. 被引量:22
  • 5王振宇.颈动脉注射甘露醇对血脑屏障通透性及甲胺喋呤人脑影响的实验研究[J].中华神经外科杂志,1987,3(3):157-157.
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