摘要
选择８例激素耐药或部分敏感的肾病综合征患儿，先给每天０．６～０．８ｇ／ｋｇ蛋白含量的低蛋白饮食（ＬＰＤ）３天，接着给每天２．５ｇ／ｋｇ高蛋白饮食（ＨＰＤ）３天。ＬＰＤ和ＨＰＤ热卡相等。试验前患儿均任意进食蛋白饮食。结果表明：ＬＰＤ后的尿蛋白较试验前显著减少。ＨＰＤ后尿蛋白、有效肾血浆流量及肾小球滤过率较ＬＰＤ后显著增加。ＬＰＤ和ＨＰＤ后的血清总蛋白、白蛋白浓度无改变。提示肾病综合征患儿不宜食ＨＰＤ。
AbstractThis study was based on eight steroid insensitivenephrotic children.The study protocol consisted oftwo successive periods of three days each. During thefitst period,the patients were fed with a low proteindiet(LPD)of 0.6～0.8g / kg / day. During the secondperiod, the patients were fed with a high protein diet(HPD) of 2.5g / kg / day.The calories provided byLPD and HPD were the same.The resultS Showed thateffective renal plasma flow,glomerular fitration rateand 24h urinary protein excretion were significantlyhigher after intake of HPD as compared to LPD. Af-ter feeding with LPD,24h urinary protein excretiondecreased significantly. Serum total protein andalbumin did not vary with the two diets,Our data sug-gest that the use of HPD in nephrotic childien shouldbe abandoned.
出处
《中华儿科杂志》
CAS
CSCD
北大核心
1994年第2期77-79,共3页
Chinese Journal of Pediatrics
