摘要
报告用转移因子（ＴＦ）、胸腺素（ＴＨ）和胎盘肽（ＰＦ）治疗哮喘病３００例，ＴＦ组１１８例，每次肌肉注射１ＩＵ，每周２次。４周后改为每周１次，连用１６～２４次；ＴＨ组和ＰＦ组分别为１３２和５０例，均每次２ｍｌ，用法同ＴＦ。疗效均以治疗前后自身对照，随访２年以上。结果表明：ＴＦ、ＴＨ和ＰＦ组的近期总有效率分别为９４．０％、９０．１％和９０．０％，其间的疗效差异无显著意义（ｘ￣２＝０．８５，Ｐ＞０．０５），远期总有效率分别为９３．０％、８７．８％和８７．６％，差异无显著意义（ｘ￣２＝２．３４，Ｐ＞０．０５）。治疗后细胞免疫指标均由治疗前的显著低于正常而升至正常范围；ＩｇＥ、ＩｇＤ治疗后明显下降，其余指标无明显变化。注射１６次以上者，细胞免疫低下，轻症及内源性哮喘患儿的疗效较好。
Abstract EffectS of TF,TH and Ff on 300 children withbronchial asthma are reported.118 cases in the TFgroup were given one IU of TF i m.twice a week inthe first 4 weeks and once a week later up to 16～24times.132 cases in the TH group and 50 cases in thePF group were given 2ml of TH or PF im.with samefrequency as in the TF group.All cases were self-con-trolled before and after treatment and followed up formore than 2 vears.Results were as follows.short-termeffects in the TF,TH and PF groups were 94.07%,90.15 and 90.00% respectively.Long-term effectswere 93.00%,87.78% and 87.50% respectively,aftertreatment,the cellular imn1unological functions in-creased significantly,while the IgE and IgD levels de-creased significantly.The course,indications andmechanisms of treatment are discussed.
出处
《中华儿科杂志》
CAS
CSCD
北大核心
1994年第2期99-101,共3页
Chinese Journal of Pediatrics
