摘要
应用两维超声心动图（ＺＤＥ）定量检测１７只开胸犬在不同程度冠状动脉左旋支（Ｌｃｘ）狭窄和心肌缺血时的局部左室收缩功能（ＲＬＶＦ）。结果显示：在静息情况下，冠脉血流量（ＣＢＦ）减少超过４０％时，２ＤＥ可检测明显的ＲＬＶＦ异常；ＣＢＦ减少８０％时，ＲＬＶＦ完全丧失。中度心肌缺血时，室壁运动异常（ＡＷＭ）的范围较局限；但严重缺血或梗塞时，ＡＷＭ的圆周范围大于Ｌｃｘ供血的心肌范围，而室壁增厚异常的圆周范围仍小于或与Ｌｃｘ供血的心肌范围基本符合。ＲＬＶＦ与ＣＢＦ减少不呈线性相关，当静息ＣＢＦ减少超过４０％时，２ＤＥ才能检测到ＲＬＶＦ异常。在定量心肌缺血时，ＲＬＶＦ异常明显早于整体左心泵功能的异常变化。
Regional left ventricular contractile function (RLVF) was quantitatively assessed by two -dimensional echocardiography (2DE) in seventeen oprn-chest dogs with different degree left circumflex (Lcx) coronary artery stenosis and acute myocardial isctemia. The results showed that as the coronary blood flow (CBF) was decreased by more than 40%, the RLVF was impaired significantly; while the decrease in CBF was over 80%, the RLVF was completely lost. The extent of abnormal wall motion (AWM) was limited in mid-myocarieal ischemia. But the circumferential extent of AWM were more than the area of Lcx blood supply in severe myocardial ischimia, the circumferential extent of abnormal Wall thickening were less and corresponded to the area of Lcx blood supply in severe myocardial ischemia and infarction. The relationship between RLVF and reduction of CBF did not show a linear, when the resting CBF decreasing was in 40% or greater. The abnormal RLVF would be sufficient magnitude to be detected by 2DE. The change in RLVF was significantly earlier than that of total left ventricular pump function in quantitative myocardial isghemia.
出处
《中华超声影像学杂志》
CSCD
1994年第1期41-44,共4页
Chinese Journal of Ultrasonography
基金
国家自然科学基金
关键词
心肌缺血
超声心动图
心室功能
two-dimensional echocardiography
myocardial ischemia
regional ventricular contractile function
