摘要
对大肠癌高发区人群筛检出来的86例大肠腺癌进行了配对病例对照(1:5)研究,发现便秘史、粘液血便史、阑尾炎史、阑尾切除史、精神刺激史及服导泻药史与大肠腺瘤有阳性联系,并具有显著的统计学意义.饮食习惯、烟酒嗜好、肠息肉史、慢性腹泻史等在大肠腺癌患者中有增高倾向,但与对照组相比,差异无显著意义.本研究为大肠癌的人群预防提供了流行病学依据.
A case-control study involving 86 patients with colorectal adenoma and 430 normal individuals as controls matched with age (5 year intervals) , sex and residency were carried out using the database collected from a population screening program for colorectal cancer in high-prevalent area. The results revealed that constipation, mucobloody stool, appendicitis, appendectomy, mental trauma and oral catharsis were significantly associated with colorectal adenoma. Dietary habits, smoking, drinking, history of colorectal polyps and chronic diarrhea were also positively associated with colorectal adenoma, but there was no statistical significance. This study provides epidemiological grounds for prevention of colorectal cancer in man.
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
1994年第12期884-887,共4页
Chinese Journal of Clinical Oncology
基金
国家"八五"科技攻关课题
关键词
大肠
腺瘤
癌前病变
危险因子
大肠肿瘤
Colorectal adenoma Precancerous lesion Risk factors Case-control study Screening program
