摘要
目的探讨妊娠期肝内胆汁淤积症孕妇血清胆汁酸水平与围生儿预后的关系。方法将95例ICP孕妇以血清胆汁酸50μmol/L为界分为A组(<50μmol/L)、B组(≥50μmol/L),回顾性分析两组在早产、胎儿宫内发育迟缓(IUGR)、死胎、羊水粪染、胎儿窘迫及新生儿预后等方面比较及其胎儿宫内窘迫、羊水粪染与临产的关系。结果B组在早产、死胎、羊水粪染、胎儿窘迫以及新生儿窒息、畸形、转科等方面发生率比A组高,差别有显著性(P<0.05),但两组IUGR发生率差别无显著性(P>0.05),且B组临产后胎儿窘迫、羊水粪染明显增多,较A组差别有显著性(P<0.05)。结论血清胆汁酸水平是预测ICP孕妇胎儿宫内情况及其预后的一个重要指标。
Objective To explore the serum total bile acid and fetal prognosis in patients with intrahepatic cholestasis of pregnancy(ICP).Methods On the base of serum total bile acid,95 patients with ICP were divided into group A(<50μmol/L)and group B(≥50μmol/L).The rate of premature delivery,intrauterine growth retardation(IUGR),fetal death,meconium-stained amniotic fluid,fetal distress and neonatal prognosis,and the relation between labor and fetal distress were analyzed retrospectively.[WTHZ]Results [WT]Premature delivery,fetal death,amniotic fluid with dung,fetal distress,neonatal asphyxia and neonatal abnormality in group A were increased significantly compared with group B(P<0.05),butIUGR in group A was alike with group B(P>0.05).After labor,patients amniotic fluid with dung,fetal distress were increased evidently compared with group B(P< 0.05).[WTHZ]Conclusion [WT]Serum total bile acid is one of important factors to evaluate the fetal condition in uterus with intrahepatic cholestasis of pregnancy.
出处
《医药论坛杂志》
2005年第10期34-35,共2页
Journal of Medical Forum
